cellexis allows continuous cultivation and expansion in one single bioreactor without passaging.
The basis for aforesaid feature is the design of the cell compartment in which the cell culture is adherently or semi-adherently cultivated.
The cell compartment is made out of one single borosilicate mold with a narrow pore size distribution (160 µm and 250 µm) and the inoculation recess.
The cell compartment is designed to enforce through capillary forces a homogeneous and reproducible distribution of the inoculum.
Therefore, the amount of the inoculated volume determines the size of the wetted surface and the used cell concentration of the suspension defines the resulting cell density on the wetted surface.
[Published on: 08.07.2011]